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Our Green Chemistry Program: Commitments and Actions

Pfizer is finding innovative ways to ease our impact on the environment during manufacturing and is continuing to "green" the process.

Goals and commitments:

  • Continue developing and applying Green Chemistry practices
  • Share Green Chemistry knowledge within our organization, as well as by educating current and future generations of scientists and engineers
  • Apply innovative science to improve world health


Notable projects embracing Green Chemistry principles:

  • "Naturalizing" Lyrica®: Taking advantage of nature's own chemical catalysts (enzymes) through biocatalysis. The enzymatic synthesis of pregabalin will save more than 200,000 metric tons of chemical waste between 2007 and 2020.
  • "Greening" Lipitor®: Manufacturing atorvastatin with a new biocatalysis process that yields significant energy savings by changing the temperature at which a reaction is performed.
  • Designed away 25,000 tons of waste per year in the manufacture of Vfend®, an antifungal medication, through a green chemistry modification in manufacturing. This novel chemistry was among finalists in 2006 for the Crystal Faraday Award.


Teams promote Green Chemistry principles through outreach activities:

  • Onsite workshops and site visits for advanced undergraduate and graduate students and their professors
  • Green Chemistry teaching curricula for middle and high schools to promote chemistry's role in addressing environmental concerns
  • Creation of a Green Chemistry Solvent Guide magnet
  • Publication of scientific papers and interviews in professional journals highlighting green chemistry benefits
  • Partnership in an industry coalition working with scientists to find greener ways to do chemistry
 


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"The industry gold standard for a pharmaceutical process in which solvent usage and recycling scenarios are considered would be the Viagra (sildenafil) process... The details of this manufacturing process were disclosed, and more importantly, significant development efforts were undertaken to set this benchmark for the pharmaceutical industry." – A Green Chemistry Comparative Analysis, authored by Michael A. Kuzemko, Susan D. Van Arnum, and Henry J. Niemczyk (Organic Process Research and Development, 2007, 11, 470-476)